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There are 2 airports in Florence. Florence Airport (FLO) is Florence’s primary airport with at least domestic flights and international flights departing from its runways every week. As of today, airlines operate out of Florence Airport (FLO). Florence Airport (FLO) is 2.6 miles from Florence and offers nonstop flights to cities. Florence’s secondary airport Myrtle Beach Intl Airport (MYR) is 59.8 miles from Florence and has airlines operating out of it and offers nonstop flights to cities with at least domestic flights and international flights departing each week.